Ablation of long noncoding RNA MALAT1 activates antioxidant pathway and alleviates sepsis in mice

Ablation of long noncoding RNA MALAT1 activates antioxidant pathway and alleviates sepsis in mice

The metastasis-associated lung adenocarcinoma transcript1 (MALAT1) is a long noncoding RNA (lncRNA) and is known for its role in cancer development and prognosis. In this study, we report that MALAT1 plays an important role in regulating acute inflammatory responses in sepsis. In patient samples, MA...

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Bibliographic Details
Main Authors: Jingshu Chen, Shu Tang, Sui Ke, James J. Cai, Daniel Osorio, Andrei Golovko, Benjamin Morpurgo, Shaodong Guo, Yuxiang Sun, Melanie Winkle, George A. Calin, Yanan Tian
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722001495

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http://www.sciencedirect.com/science/article/pii/S2213231722001495

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