Synthesis, characterization, and radiosynthesis of fluorine-18-AVT-011 as a Pgp chemoresistance imaging marker

Synthesis, characterization, and radiosynthesis of fluorine-18-AVT-011 as a Pgp chemoresistance imaging marker

Abstract P-glycoprotein (Pgp) is the most studied ATP-binding cassette (ABC) efflux transporter and contributes to chemoresistance. A few tracers have been developed to detect the in-vivo status of chemoresistance using positron emission tomography (PET) imaging. In our study, we have synthesized la...

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Bibliographic Details
Main Authors: Pardeep Kumar, Riptee Thakur, Pratap Chandra Acharya, Hosahalli K. Mohan, U. N. Pallavi, Divya Maheshwari, Afsal Mohammed K M, Aishwarya Kumar, Sridhar Goud Nerella, Raman Kumar Joshi, Manoj Kumar, Chandana Nagaraj
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-22930-6

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https://doi.org/10.1038/s41598-022-22930-6

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