Intake of <i>Lactobacillus delbrueckii</i> (pExu:<i>hsp65</i>) Prevents the Inflammation and the Disorganization of the Intestinal Mucosa in a Mouse Model of Mucositis

Intake of <i>Lactobacillus delbrueckii</i> (pExu:<i>hsp65</i>) Prevents the Inflammation and the Disorganization of the Intestinal Mucosa in a Mouse Model of Mucositis

5-Fluorouracil (5-FU) is an antineoplastic drug that causes, as a side effect, intestinal mucositis, acute inflammation in the small bowel. The Heat Shock Protein (Hsp) are highly expressed in inflammatory conditions, developing an important role in immune modulation. Thus, they are potential candid...

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Bibliographic Details
Main Authors: Fernanda Alvarenga Lima Barroso, Luís Cláudio Lima de Jesus, Camila Prosperi de Castro, Viviane Lima Batista, Ênio Ferreira, Renata Salgado Fernandes, André Luís Branco de Barros, Sophie Yvette Leclerq, Vasco Azevedo, Pamela Mancha-Agresti, Mariana Martins Drumond
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Microorganisms
Subjects:
recombinant probiotics
DNA delivery
intestinal mucositis
inflammation
technetium-99m
bacterial translocation
Online Access:https://www.mdpi.com/2076-2607/9/1/107

Internet

https://www.mdpi.com/2076-2607/9/1/107

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