Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC) shows many entrapped pro-inflammatory molecules that may also contribute to a failed fibrinolytic system

Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC) shows many entrapped pro-inflammatory molecules that may also contribute to a failed fibrinolytic system

Abstract Background Post-acute sequelae of COVID-19 (PASC), also now known as long COVID, has become a major global health and economic burden. Previously, we provided evidence that there is a significant insoluble fibrin amyloid microclot load in the circulation of individuals with long COVID, and...

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Bibliographic Details
Main Authors: Arneaux Kruger, Mare Vlok, Simone Turner, Chantelle Venter, Gert Jacobus Laubscher, Douglas B. Kell, Etheresia Pretorius
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Cardiovascular Diabetology
Subjects:
Long COVID
Microclots
Platelet hyperactivation
von Willebrand factor
Kallikrein
Platelet factor 4
Online Access:https://doi.org/10.1186/s12933-022-01623-4

Internet

https://doi.org/10.1186/s12933-022-01623-4

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