Hydrogen Peroxide Stimulates the LPS-induced Tetrahydrobiopterin Synthesis in Mouse Brain Microvascular Endothelial Cells
Tetrahydrobiopterin (BH4) is one of the cofactors for nitric oxide synthase (NOS), and also has a protective effect against reactive oxygen species (ROS)- and/or nitric oxide (NO)-induced cytotoxicities. Lipopolysaccharide (LPS) induces NO production and BH4 synthesis, and also ROS release. This stu...
Главные авторы: | , , , , , , |
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Формат: | Статья |
Язык: | English |
Опубликовано: |
De Gruyter
2002-02-01
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Серии: | Pteridines |
Предметы: | |
Online-ссылка: | https://doi.org/10.1515/pteridines.2002.13.1.21 |