Synthesis, in silico and in vitro antimicrobial efficacy of substituted arylidene-based quinazolin-4(3H)-one motifs

Synthesis, in silico and in vitro antimicrobial efficacy of substituted arylidene-based quinazolin-4(3H)-one motifs

Introduction: Quinazolin-4(3H)-one derivatives have attracted considerable attention in the pharmacological profiling of therapeutic drug targets. The present article reveals the development of arylidene-based quinazolin-4(3H)-one motifs as potential antimicrobial drug candidates.Methods: The synthe...

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Bibliographic Details
Main Authors: Gbolahan O. Oduselu, Damilola V. Aderohunmu, Olayinka O. Ajani, Oluwadunni F. Elebiju, Temitope A. Ogunnupebi, Ezekiel Adebiyi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Chemistry
Subjects:
ADMET
antibacterial activities
antifungal activities
bioactive analog
hydrazone
inhibition
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2023.1264824/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2023.1264824/full

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