Protein imbalance in the development of skeletal muscle wasting in tumour‐bearing mice

Protein imbalance in the development of skeletal muscle wasting in tumour‐bearing mice

Abstract Background Cancer cachexia occurs in approximately 80% of cancer patients and is a key contributor to cancer‐related death. The mechanisms controlling development of tumour‐induced muscle wasting are not fully elucidated. Specifically, the progression and development of cancer cachexia are...

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Bibliographic Details
Main Authors: Jacob L. Brown, David E. Lee, Megan E. Rosa‐Caldwell, Lemuel A. Brown, Richard A. Perry, Wesley S. Haynie, Kendra Huseman, Kavithalakshmi Sataranatarajan, Holly Van Remmen, Tyrone A. Washington, Michael P. Wiggs, Nicholas P. Greene
Format: Article
Language:English
Published: Wiley 2018-10-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Protein synthesis
LLC
Ubiquitin
MAPK
ERK
p38
Online Access:https://doi.org/10.1002/jcsm.12354

Internet

https://doi.org/10.1002/jcsm.12354

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