Multi-scale mechanobiological model for skeletal muscle hypertrophy

Skeletal muscle adaptation is correlated to training exercise by triggering different signaling pathways that target many functions; in particular, the IGF1-AKT pathway controls protein synthesis and degradation. These two functions regulate the adaptation in size and strength of muscles. Computatio...

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Bibliographic Details
Main Authors: Yesid Villota-Narvaez, Diego A. Garzón-Alvarado, Oliver Röhrle, Angelica M. Ramírez-Martínez
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.899784/full