Injectable kartogenin and apocynin loaded micelle enhances the alleviation of intervertebral disc degeneration by adipose-derived stem cell

Injectable kartogenin and apocynin loaded micelle enhances the alleviation of intervertebral disc degeneration by adipose-derived stem cell

Cell transplantation has been proved the promising therapeutic effects on intervertebral disc degeneration (IVDD). However, the increased levels of reactive oxygen species (ROS) in the degenerated region will impede the efficiency of human adipose-derived stem cells (human ADSCs) transplantation the...

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Bibliographic Details
Main Authors: Chao Yu, Dongdong Li, Chenggui Wang, Kaishun Xia, Jingkai Wang, Xiaopeng Zhou, Liwei Ying, Jiawei Shu, Xianpeng Huang, Haibin Xu, Bin Han, Qixin Chen, Fangcai Li, Jianbin Tang, Chengzhen Liang, Nigel Slater
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-10-01
Series:Bioactive Materials
Subjects:
Intervertebral disc degeneration
Polymer-drug conjugates
Mesenchymal stem cell
Reactive oxygen species
Stem cell therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21001298

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http://www.sciencedirect.com/science/article/pii/S2452199X21001298

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