Performance Comparison of Recombinant Baculovirus and Rabies Virus-like Particles production Using Two Culture Platforms

Performance Comparison of Recombinant Baculovirus and Rabies Virus-like Particles production Using Two Culture Platforms

This work aimed to assess, following upstream optimization in Schott flasks, the scalability from this culture platform to a stirred-tank bioreactor in order to yield rabies-recombinant baculovirus, bearing genes of G (BVG) and M (BVM) proteins, and to obtain rabies virus-like particles (VLP) from t...

Full description

Bibliographic Details
Main Authors: Luis Giovani Oliveira Guardalini, Paulo Eduardo da Silva Cavalcante, Jaci Leme, Renata Gois de Mello, Thaissa Consoni Bernardino, Simone Gonçalves Silva Jared, Marta Maria Antoniazzi, Renato Mancini Astray, Aldo Tonso, Eutimio Gustavo Fernández Núñez, Soraia Attie Calil Jorge
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Vaccines
Subjects:
rabies virus-like particles
recombinant baculovirus
Sf9 cells
stirred-tank bioreactor
viral infection
quality by design
Online Access:https://www.mdpi.com/2076-393X/11/1/39

Internet

https://www.mdpi.com/2076-393X/11/1/39

Similar Items