The Key Gene Expression Patterns and Prognostic Factors in Malignant Transformation from Enchondroma to Chondrosarcoma

The Key Gene Expression Patterns and Prognostic Factors in Malignant Transformation from Enchondroma to Chondrosarcoma

Enchondroma (EC) is a common benign bone tumor. It has the risk of malignant transformation to Chondrosarcoma (CS). However, the underlying mechanism is unclear. The gene expression profile of EC and CS was obtained from Gene Expression Omnibus (GEO) database. The differentially expressed genes (DEG...

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Bibliographic Details
Main Authors: Junqing Wu, Yue Huang, Chengxuan Yu, Xia Li, Limengmeng Wang, Jundong Hong, Daochao Lin, Xiaoping Han, Guoji Guo, Tianye Hu, He Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
enchondroma
chondrosarcoma
epithelial to mesenchymal transformation
VEGFA-VEGF2R signaling pathway
T cell immunity
angiogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.693034/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.693034/full

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