Expanding the search for germline pathogenic variants for breast cancer. How far should we go and how high should we jump? The missed opportunity!

Since the identification of BRCA1 and BRCA2 genes 3 decades ago, genetic testing and genetic counseling have become an integral part of routine clinical practice. The risk of breast cancer among carriers of germline pathogenic variants, like BRCA1 and BRCA2, is well established. Risk-reducing interv...

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Bibliographic Details
Main Author: Hikmat Abdel-Razeq
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Oncology Reviews
Subjects:
Online Access:https://oncologyreviews.org/site/article/view/544