Transcriptomic evidence for immaturity induced by antidepressant fluoxetine in the hippocampus and prefrontal cortex

Abstract Aims The molecular and cellular mechanisms underlying the antidepressant effects of fluoxetine in the brain are not fully understood. Emerging evidence has led to the hypothesis that chronic fluoxetine treatment induces dematuration of certain types of mature neurons in rodents. These studi...

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Bibliographic Details
Main Authors: Hideo Hagihara, Koji Ohira, Tsuyoshi Miyakawa
Format: Article
Language:English
Published: Wiley 2019-06-01
Series:Neuropsychopharmacology Reports
Online Access:https://doi.org/10.1002/npr2.12048