Multiplexed Target Enrichment Enables Efficient and In-Depth Analysis of Antimicrobial Resistome in Metagenomes

Multiplexed Target Enrichment Enables Efficient and In-Depth Analysis of Antimicrobial Resistome in Metagenomes

ABSTRACT Antibiotic resistance genes (ARGs) pose a serious threat to public health and ecological security in the 21st century. However, the resistome only accounts for a tiny fraction of metagenomic content, which makes it difficult to investigate low-abundance ARGs in various environmental setting...

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Bibliographic Details
Main Authors: Yiming Li, Xiaomin Shi, Yang Zuo, Tian Li, Lu Liu, Zhangqi Shen, Jianzhong Shen, Rong Zhang, Shaolin Wang
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:Microbiology Spectrum
Subjects:
resistome
targeted amplification
high-throughput sequencing
metagenomics
SNPs
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02297-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.02297-22

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