The role of mesenchymal stem cells in hematopoietic stem cell transplantation: prevention and treatment of graft-versus-host disease

Abstract Background The use and effectiveness of hematopoietic stem cell transplantation (HSCT) are limited by lethal complications, i.e., acute and chronic graft-versus-host disease (aGVHD and cGVHD, respectively), in which immune cells from the donor attack healthy recipient tissues. GVHD presents...

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Bibliographic Details
Main Authors: Lu Zhao, Shanquan Chen, Panxin Yang, Hongcui Cao, Lanjuan Li
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13287-019-1287-9