Lipocalin 2 modulates dendritic cell activity and shapes immunity to influenza in a microbiome dependent manner.

Lipocalin 2 modulates dendritic cell activity and shapes immunity to influenza in a microbiome dependent manner.

Lipocalin 2 (LCN2) is a secreted glycoprotein with roles in multiple biological processes. It contributes to host defense by interference with bacterial iron uptake and exerts immunomodulatory functions in various diseases. Here, we aimed to characterize the function of LCN2 in lung macrophages and...

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Bibliographic Details
Main Authors: Martin L Watzenboeck, Barbara Drobits, Sophie Zahalka, Anna-Dorothea Gorki, Asma Farhat, Federica Quattrone, Anastasiya Hladik, Karin Lakovits, Gabriel M Richard, Therese Lederer, Birgit Strobl, Gijs A Versteeg, Louis Boon, Philipp Starkl, Sylvia Knapp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009487

Internet

https://doi.org/10.1371/journal.ppat.1009487

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