Dose-dependent stimulation of human follicular steroidogenesis by a novel rhCG during ovarian stimulation with fixed rFSH dosing

Dose-dependent stimulation of human follicular steroidogenesis by a novel rhCG during ovarian stimulation with fixed rFSH dosing

BackgroundChoriogonadotropin (CG) beta (FE 999302), a novel recombinant human (h)CG produced by a human cell line, has a longer half-life and higher potency than CG alfa produced by a Chinese hamster ovary cell line. hCG augments steroid production, but the extent of which CG beta treatment during o...

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Bibliographic Details
Main Authors: Jane Alrø Bøtkjær, Stine Gry Kristensen, Hanna Ørnes Olesen, Per Larsson, Bernadette Mannaerts, Claus Yding Andersen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Endocrinology
Subjects:
Steroidogenesis
FE 999302
recombinant hCG
ovarian stimulation
cumulus cells
single nucleotide polymorphisms
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1004596/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.1004596/full

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