ERK Inhibition Promotes Engraftment of Allografts by Reprogramming T‐Cell Metabolism

ERK Inhibition Promotes Engraftment of Allografts by Reprogramming T‐Cell Metabolism

Abstract Extracellular regulated protein kinases (ERK) signaling is a master regulator of cell behavior, life, and fate. Although ERK pathway is shown to be involved in T‐cell activation, little is known about its role in the development of allograft rejection. Here, it is reported that ERK signalin...

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Bibliographic Details
Main Authors: Xiaosheng Tan, Changxing Qi, Xiangli Zhao, Lingjuan Sun, Mi Wu, Weiguang Sun, Lianghu Gu, Fengqing Wang, Hao Feng, Xia Huang, Bin Xie, Zhengyi Shi, Peiling Xie, Meng Wu, Yonghui Zhang, Gang Chen
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Advanced Science
Subjects:
allograft rejection
extracellular regulated protein kinases (ERK)
lycorine
metabolism
mitochondria
Online Access:https://doi.org/10.1002/advs.202206768

Internet

https://doi.org/10.1002/advs.202206768

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