Update and elucidation of Plasmodium kinomes: Prioritization of kinases as potential drug targets for malaria

Update and elucidation of Plasmodium kinomes: Prioritization of kinases as potential drug targets for malaria

Malaria is a tropical disease caused by Plasmodium spp. and transmitted by the bite of infected Anopheles mosquitoes. Protein kinases (PKs) play key roles in the life cycle of the etiological agent of malaria, turning these proteins attractive targets for antimalarial drug discovery campaigns. As pa...

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Bibliographic Details
Main Authors: Joyce Villa Verde Bastos Borba, Arthur de Carvalho e Silva, Marília Nunes do Nascimento, Letícia Tiburcio Ferreira, Aline Rimoldi, Luísa Starling, Pablo Ivan Pereira Ramos, Fabio Trindade Maranhão Costa, Carolina Horta Andrade
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Plasmodium
Protein kinase
Malaria
Kinome
Target prioritization
Drug discovery
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022002835

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http://www.sciencedirect.com/science/article/pii/S2001037022002835

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