Transcriptional profiling sheds light on the fibrotic aspects of idiopathic subglottic tracheal stenosis

Transcriptional profiling sheds light on the fibrotic aspects of idiopathic subglottic tracheal stenosis

Idiopathic subglottic stenosis (ISGS) is a rare fibrotic disease of the upper trachea with an unknown pathomechanism. It typically affects adult Caucasian female patients, leading to severe airway constrictions caused by progressive scar formation and inflammation with clinical symptoms of dyspnoea,...

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Bibliographic Details
Main Authors: Martin Direder, Maria Laggner, Dragan Copic, Katharina Klas, Daniel Bormann, Thomas Schweiger, Konrad Hoetzenecker, Clemens Aigner, Hendrik Jan Ankersmit, Michael Mildner
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
idiopathic subglottic stenosis
trachea
matrix
fibroblasts
plasma cells
Schwann cells
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1380902/full

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https://www.frontiersin.org/articles/10.3389/fcell.2024.1380902/full

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