Integrative analysis of single-cell and bulk RNA-sequencing data revealed T cell marker genes based molecular sub-types and a prognostic signature in lung adenocarcinoma

Integrative analysis of single-cell and bulk RNA-sequencing data revealed T cell marker genes based molecular sub-types and a prognostic signature in lung adenocarcinoma

Abstract Immunotherapy has emerged as a promising modality for addressing advanced or conventionally drug-resistant malignancies. When it comes to lung adenocarcinoma (LUAD), T cells have demonstrated significant influence on both antitumor activity and the tumor microenvironment. However, their spe...

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Bibliographic Details
Main Authors: Yueling Peng, Yafang Dong, Qihui Sun, Yue Zhang, Xiangyang Zhou, Xiaoyang Li, Yuehong Ma, Xingwei Liu, Rongshan Li, Fengjie Guo, Lili Guo
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-50787-w

Internet

https://doi.org/10.1038/s41598-023-50787-w

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