Emerging epigenetic therapeutics for myeloid leukemia: modulating demethylase activity with ascorbate
The past decade has seen a proliferation of drugs that target epigenetic pathways. Many of these drugs were developed to treat acute myeloid leukemia, a condition in which dysregulation of the epigenetic landscape is well established. While these drugs have shown promise, critical issues persist. S...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Ferrata Storti Foundation
2020-10-01
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Series: | Haematologica |
Online Access: | https://haematologica.org/article/view/10064 |