HSF-1: Guardian of the Proteome Through Integration of Longevity Signals to the Proteostatic Network

Discoveries made in the nematode Caenorhabditis elegans revealed that aging is under genetic control. Since these transformative initial studies, C. elegans has become a premier model system for aging research. Critically, the genes, pathways, and processes that have fundamental roles in organismal...

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Bibliographic Details
Main Authors: Maria I. Lazaro-Pena, Zachary C. Ward, Sifan Yang, Alexandra Strohm, Alyssa K. Merrill, Celia A. Soto, Andrew V. Samuelson
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Aging
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fragi.2022.861686/full