A recombinant rabies virus chimera expressing the DC-targeting molecular MAB2560 shows enhanced vaccine immunogenicity through activation of dendritic cells.

<h4>Background</h4>Rabies, caused by the rabies virus (RABV), is an ancient and neglected zoonotic disease posing a large public health threat to humans and animals in developing countries. Immunization of animals with a rabies vaccine is the most effective way to control the epidemic an...

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Main Authors: Zhiyuan Gong, Pei Huang, Hongli Jin, Yujie Bai, Hailun Li, Meichen Qian, Jingxuan Sun, Cuicui Jiao, Mengyao Zhang, Yuanyuan Li, Haili Zhang, Hualei Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-04-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0011254