IgE glycans promote anti-IgE IgG autoantibodies that facilitate IgE serum clearance via Fc Receptors
BackgroundRecent studies have shown that IgE glycosylation significantly impacts the ability of IgE to bind to its high-affinity receptor FcεRI and exert effector functions. We have recently demonstrated that immunizing mice with IgE in a complex with an allergen leads to a protective, glycan-depend...
| Hauptverfasser: | , , , , , |
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| Format: | Artikel |
| Sprache: | English |
| Veröffentlicht: |
Frontiers Media S.A.
2022-12-01
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| Schriftenreihe: | Frontiers in Immunology |
| Schlagworte: | |
| Online Zugang: | https://www.frontiersin.org/articles/10.3389/fimmu.2022.1069100/full |