Non-selective cation channels mediate chloroquine-induced relaxation in precontracted mouse airway smooth muscle.

Non-selective cation channels mediate chloroquine-induced relaxation in precontracted mouse airway smooth muscle.

Bitter tastants can induce relaxation in precontracted airway smooth muscle by activating big-conductance potassium channels (BKs) or by inactivating voltage-dependent L-type Ca2+ channels (VDLCCs). In this study, a new pathway for bitter tastant-induced relaxation was defined and investigated. We f...

Descripción completa

Detalles Bibliográficos
Autores principales: Ting Zhang, Xiao-Jing Luo, Wen-Bo Sai, Meng-Fei Yu, Wen-Er Li, Yun-Fei Ma, Weiwei Chen, Kui Zhai, Gangjian Qin, Donglin Guo, Yun-Min Zheng, Yong-Xiao Wang, Jin-Hua Shen, Guangju Ji, Qing-Hua Liu
Formato: Artículo
Lenguaje:English
Publicado: Public Library of Science (PLoS) 2014-01-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC4081631?pdf=render

Internet

http://europepmc.org/articles/PMC4081631?pdf=render

Ejemplares similares