Palmatine, a Bioactive Protoberberine Alkaloid Isolated from <i>Berberis cretica</i>, Inhibits the Growth of Human Estrogen Receptor-Positive Breast Cancer Cells and Acts Synergistically and Additively with Doxorubicin

Palmatine, a Bioactive Protoberberine Alkaloid Isolated from <i>Berberis cretica</i>, Inhibits the Growth of Human Estrogen Receptor-Positive Breast Cancer Cells and Acts Synergistically and Additively with Doxorubicin

Palmatine (PLT) is a natural isoquinoline alkaloid that belongs to the class of protoberberines and exhibits a wide spectrum of pharmacological and biological properties, including anti-cancer activity. The aim of our study was to isolate PLT from the roots of <i>Berberis cretica</i> and...

Full description

Bibliographic Details
Main Authors: Aneta Grabarska, Paula Wróblewska-Łuczka, Wirginia Kukula-Koch, Jarogniew J. Łuszczki, Eleftherios Kalpoutzakis, Grzegorz Adamczuk, Alexios Leandros Skaltsounis, Andrzej Stepulak
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Molecules
Subjects:
palmatine
isoquinoline alkaloids
<i>Berberis cretica</i>
Berberidaceae
breast cancer
isobolographic analysis
Online Access:https://www.mdpi.com/1420-3049/26/20/6253

Internet

https://www.mdpi.com/1420-3049/26/20/6253

Similar Items