Identification of HPV16-p16INK4a mediated methylation in oral potentially malignant disorder

To evaluate the possible involvement of epigenetic modulation by HPV16-p16INK4a in oral potentially malignant disorder (OPMD). We generated DNA-methylation profiles, according to p16INK4a expression and HPV16 genotype (positive or negative), of OPMD samples and p16INK4a-HPV16 negative samples (used...

Full description

Bibliographic Details
Main Authors: Maria Rosa Buenahora, Gloria Inés Lafaurie, Sandra J. Perdomo
Format: Article
Language:English
Published: Taylor & Francis Group 2021-09-01
Series:Epigenetics
Subjects:
Online Access:http://dx.doi.org/10.1080/15592294.2020.1834923