Pteryxin suppresses osteoclastogenesis and prevents bone loss via inhibiting the MAPK/Ca2+ signaling pathways mediated by ROS

Pteryxin suppresses osteoclastogenesis and prevents bone loss via inhibiting the MAPK/Ca2+ signaling pathways mediated by ROS

Osteoporosis, as a severe public health problem worldwide, causes systemic damage to bone mass, strength, and microstructure with an increased propensity for fragility fractures. Given the inherent adverse effects associated with long-term use of current prescription medications for osteoporosis tre...

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Bibliographic Details
Main Authors: Ran Sun, Na Hai, Biao Yang, JunChun Chen, Jing Li, Qiufei Li, Jinmin Zhao, Jiake Xu, Qian Liu, Bo Zhou
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Pteryxin
Osteoclast
ROS
MAPK
Ca2+
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223006881

Internet

http://www.sciencedirect.com/science/article/pii/S0753332223006881

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