Upregulation of endocytic protein expression in the Alzheimer’s disease male human brain

Amyloid-beta (Aβ) is produced from amyloid precursor protein (APP) primarily after APP is internalised by endocytosis and clathrin-mediated endocytic processes are altered in Alzheimer’s disease (AD). There is also evidence that cholesterol and flotillin affect APP endocytosis. We hypothesised that...

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Bibliographic Details
Main Authors: Mouhamed Alsaqati, Rhian S. Thomas, Emma J. Kidd
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Aging Brain
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258995892300021X