Modifications in cellular viability, DNA damage and stress responses inflicted in cancer cells by copper-64 ions

Modifications in cellular viability, DNA damage and stress responses inflicted in cancer cells by copper-64 ions

Due to combined therapeutical emissions, a high linear energy transfer Auger-electrons with the longer ranged β− particles, 64Cu-based radiopharmaceuticals raise particular theragnostic interest in cancer, by joined therapeutic and real-time PET imaging properties. The in vitro study aimed to invest...

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Bibliographic Details
Main Authors: Radu M. Serban, Dana Niculae, Gina Manda, Ionela Neagoe, Maria Dobre, Dragoș A. Niculae, Mihaela Temelie, Cosmin Mustăciosu, Radu A. Leonte, Livia E. Chilug, Maria R. Cornoiu, Diana Cocioabă, Miruna Stan, Anca Dinischiotu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Medicine
Subjects:
auger-electrons
copper-64
radiotherapy
radiotoxicity
stress response
theragnostic
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1197846/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2023.1197846/full

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