Antibody-antibiotic conjugate targeted therapy for orthopedic implant-associated intracellular S. aureus infections

Antibody-antibiotic conjugate targeted therapy for orthopedic implant-associated intracellular S. aureus infections

Introduction: Treating orthopedic implant-associated infections, especially those caused by Staphylococcus aureus (S. aureus), remains a significant challenge. S. aureus has the ability to invade host cells, enabling it to evade both antibiotics and immune responses during infection, which may resul...

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Bibliographic Details
Main Authors: Leilei Qin, Ning Hu, Yanhao Zhang, Jianye Yang, Liqun Zhao, Xiaokai Zhang, Yun Yang, Jinyong Zhang, Yinshuang Zou, Keyu Wei, Chen Zhao, Yujian Li, Hao Zeng, Wei Huang, Quanming Zou
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Journal of Advanced Research
Subjects:
Periprosthetic joint infection
staphylococcal protein A
Staphylococcus aureus intracellular infection
Antibody-antibiotic conjugate
Antibody-drug conjugate
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123223003752

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http://www.sciencedirect.com/science/article/pii/S2090123223003752

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