Antiviral drug discovery by targeting the SARS-CoV-2 polyprotein processing by inhibition of the main protease

The spread of SARS-CoV-2, the causative agent for COVID-19, has led to a global and deadly pandemic. To date, few drugs have been approved for treating SARS-CoV-2 infections. In this study, a structure-based approach was adopted using the SARS-CoV-2 main protease (Mpro) and a carefully selected data...

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Bibliographic Details
Main Authors: Mahmoud Kandeel, Jinsoo Kim, Mahmoud Fayez, Yukio Kitade, Hyung-Joo Kwon
Format: Article
Language:English
Published: PeerJ Inc. 2022-02-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/12929.pdf