Structural model analysis of multiple quantitative traits.

We introduce a method for the analysis of multilocus, multitrait genetic data that provides an intuitive and precise characterization of genetic architecture. We show that it is possible to infer the magnitude and direction of causal relationships among multiple correlated phenotypes and illustrate...

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Bibliographic Details
Main Authors: Renhua Li, Shirng-Wern Tsaih, Keith Shockley, Ioannis M Stylianou, Jon Wergedal, Beverly Paigen, Gary A Churchill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1513264?pdf=render