Maternally inherited coronary heart disease is associated with a novel mitochondrial tRNA mutation

Abstract Background Coronary heart disease (CHD) is the most common cause of mortality globally, yet mitochondrial genetic mutations associated with CHD development remain incompletely understood. Methods The subjects from three Chinese families with LHON underwent clinical, genetic, molecular, and...

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Bibliographic Details
Main Authors: Zhenxiao Zhang, Mingyang Liu, Jianshuai He, Xiaotian Zhang, Yuehua Chen, Hui Li
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Cardiovascular Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12872-019-01284-4