Maternally inherited coronary heart disease is associated with a novel mitochondrial tRNA mutation
Abstract Background Coronary heart disease (CHD) is the most common cause of mortality globally, yet mitochondrial genetic mutations associated with CHD development remain incompletely understood. Methods The subjects from three Chinese families with LHON underwent clinical, genetic, molecular, and...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-12-01
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Series: | BMC Cardiovascular Disorders |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12872-019-01284-4 |