Dapsone reduced cuprizone-induced demyelination via targeting Nrf2 and IKB in C57BL/6 mice

Dapsone reduced cuprizone-induced demyelination via targeting Nrf2 and IKB in C57BL/6 mice

Objective(s): Multiple Sclerosis (MS) is an inflammatory disorder wherein the myelin of nerve cells in the central nervous system is damaged. In the current study, we assessed the effect of Dapsone (DAP) on the improvement of behavioral dysfunction and preservation of myelin in the cuprizone (CPZ) i...

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Bibliographic Details
Main Authors: Ahmad Reza Dehpour, Ehsan Khaledi, Tayebeh Noori, Ahmad Mohammadi-Farani, Ladan Delphi, Antoni Sureda, Eduardo Sobarzo-Sanchez, Samira Shirooie
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2022-06-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
cuprizone
dapsone
multiple sclerosis neuroinflammation
nf-kb
nrf2
Online Access:https://ijbms.mums.ac.ir/article_20411_ca35acc398c7ce118f36cf961ecc7891.pdf

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https://ijbms.mums.ac.ir/article_20411_ca35acc398c7ce118f36cf961ecc7891.pdf

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