The Keap1/Nrf2/ARE system activators do not increase cardiac resistance to long-term ischemia/reperfusion

The Keap1/Nrf2/ARE system activators do not increase cardiac resistance to long-term ischemia/reperfusion

Oxidative stress is an important mechanism of myocardial damage during ischemia/reperfusion. To investigate the possibility of restoring the redox balance using “indirect” antioxidant effects, the cardioprotective effect Keap1/Nrf2/ ARE system inducers was studied in long-term ischemia/reperfusion i...

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Bibliographic Details
Main Authors: P. M. Kozhin, A. S. Sementsov, S. E. Khrapov, M. V. Khrapova, L. P. Romakh, N. V. Kandalintseva, E. B. Menshchikova
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Siberian Branch Publishing House 2022-12-01
Series:Сибирский научный медицинский журнал
Subjects:
ischemia
reperfusion
myocardial injury
reactive oxygen species
antioxidants
keap1/nrf2/are signaling system
Online Access:https://sibmed.elpub.ru/jour/article/view/932

Internet

https://sibmed.elpub.ru/jour/article/view/932

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