An update on clonality: what smooth muscle cell type makes up the atherosclerotic plaque? [version 1; referees: 2 approved]

Almost 50 years ago, Earl Benditt and his son John described the clonality of the atherosclerotic plaque. This led Benditt to propose that the atherosclerotic lesion was a smooth muscle neoplasm, similar to the leiomyomata seen in the uterus of most women. Although the observation of clonality has b...

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Bibliographic Details
Main Authors: Stephen M. Schwartz, Renu Virmani, Mark W. Majesky
Format: Article
Language:English
Published: F1000 Research Ltd 2018-12-01
Series:F1000Research
Online Access:https://f1000research.com/articles/7-1969/v1