Does synaptic hypometabolism or synaptic dysfunction, originate cognitive loss? Analysis of the evidence

Abstract Elderly persons with currently normal cognition who have cerebral hypometabolism as shown by low uptake of 18fluorine‐fluorodeoxyglucose (18F‐FDG), are at risk of future loss of cognition and, thus, of future Alzheimer's dementia (AD). Reduction of either 18F‐FDG or cognition is assume...

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Bibliographic Details
Main Author: Jeffrey Fessel
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Subjects:
Online Access:https://doi.org/10.1002/trc2.12177