Butyrate Treatment of DSS-Induced Ulcerative Colitis Affects the Hepatic Drug Metabolism in Mice

Butyrate Treatment of DSS-Induced Ulcerative Colitis Affects the Hepatic Drug Metabolism in Mice

The development of inflammatory bowel disease (IBD) is associated with alterations in the gut microbiota. There is currently no universal treatment for this disease, thus emphasizing the importance of developing innovative therapeutic approaches. Gut microbiome-derived metabolite butyrate with its w...

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Bibliographic Details
Main Authors: Lenka Jourova, Stefan Satka, Veronika Frybortova, Iveta Zapletalova, Pavel Anzenbacher, Eva Anzenbacherova, Petra Petr Hermanova, Barbora Drabonova, Dagmar Srutkova, Hana Kozakova, Tomas Hudcovic
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Pharmacology
Subjects:
gut–liver axis
butyrate
gut inflammation
drug metabolism
cytochromes P450
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.936013/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.936013/full

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