Structural Basis of Artemisinin Binding Sites in Serum Albumin with the Combined Use of NMR and Docking Calculations

Structural Basis of Artemisinin Binding Sites in Serum Albumin with the Combined Use of NMR and Docking Calculations

Artemisinin is known to bind to the main plasma protein carrier serum albumin (SA); however, there are no atomic level structural data regarding its binding mode with serum albumin. Herein, we employed a combined strategy of saturation transfer difference (STD), transfer nuclear Overhauser effect sp...

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Bibliographic Details
Main Authors: Alexandra Primikyri, Georgios Papamokos, Themistoklis Venianakis, Marianna Sakka, Vassiliki G. Kontogianni, Ioannis P. Gerothanassis
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Molecules
Subjects:
artemisinin
serum albumin
STD NMR
STD-TOCSY NMR
TR-NOESY NMR
INPHARMA NMR
Online Access:https://www.mdpi.com/1420-3049/27/18/5912

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https://www.mdpi.com/1420-3049/27/18/5912

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