Targeting Key Signaling Pathways in Glioblastoma Stem Cells for the Development of Efficient Chemo- and Immunotherapy

Targeting Key Signaling Pathways in Glioblastoma Stem Cells for the Development of Efficient Chemo- and Immunotherapy

Glioblastoma multiforme (GBM) is the most aggressive and most common malignant brain tumor with poor patient survival despite therapeutic intervention. On the cellular level, GBM comprises a rare population of glioblastoma stem cells (GSCs), driving therapeutic resistance, invasion, and recurrence....

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Bibliographic Details
Main Authors: Laureen P. Helweg, Jonathan Storm, Kaya E. Witte, Wiebke Schulten, Lennart Wrachtrup, Till Janotte, Angelika Kitke, Johannes F. W. Greiner, Cornelius Knabbe, Barbara Kaltschmidt, Matthias Simon, Christian Kaltschmidt
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
glioblastoma multiforme
cancer stem cells
NF-κB
MYC
NK-cells
chemotherapy
Online Access:https://www.mdpi.com/1422-0067/23/21/12919

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https://www.mdpi.com/1422-0067/23/21/12919

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