Effects of D-Serine and MK-801 on Neuropathic Pain and Functional Recovery in a Rat Model of Spinal Cord Injury

Effects of D-Serine and MK-801 on Neuropathic Pain and Functional Recovery in a Rat Model of Spinal Cord Injury

Objective Neuropathic pain is a common secondary complication of spinal cord injury (SCI). N-methyl-D-aspartate (NMDA) receptor activation is critical for hypersensitivity in neuropathic pain. This activation requires the binding of both glutamate and the D-serine co-agonist to the NMDA glycine site...

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Bibliographic Details
Main Authors: Dongwoo Yu, Seul Ah Mun, Sang Woo Kim, Dae-Chul Cho, Chi Heon Kim, Inbo Han, Subum Lee, Sang-Woo Lee, Kyoung-Tae Kim
Format: Article
Language:English
Published: Korean Spinal Neurosurgery Society 2022-09-01
Series:Neurospine
Subjects:
serine
mk-801
nmda
spinal cord injuries
neuropathic pain
Online Access:http://e-neurospine.org/upload/pdf/ns-2244410-205.pdf

Internet

http://e-neurospine.org/upload/pdf/ns-2244410-205.pdf

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