ALDH2 variance in disease and populations

The ALDH2*2 missense variant that commonly causes alcohol flushing reactions is the single genetic polymorphism associated with the largest number of traits in humans. The dysfunctional ALDH2 variant affects nearly 8% of the world population and is highly concentrated among East Asians. Carriers of...

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Bibliographic Details
Main Authors: Che-Hong Chen, Benjamin R. Kraemer, Daria Mochly-Rosen
Format: Article
Language:English
Published: The Company of Biologists 2022-06-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/15/6/dmm049601