ALDH2 variance in disease and populations
The ALDH2*2 missense variant that commonly causes alcohol flushing reactions is the single genetic polymorphism associated with the largest number of traits in humans. The dysfunctional ALDH2 variant affects nearly 8% of the world population and is highly concentrated among East Asians. Carriers of...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2022-06-01
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Series: | Disease Models & Mechanisms |
Online Access: | http://dmm.biologists.org/content/15/6/dmm049601 |