Sunitinib malate induces cell death in adult human cardiac progenitor cells

Sunitinib malate is known to cause cardiotoxicity in a sub-population of patients, with heart failure seen in more severe cases. Cardiac progenitor cells (CPCs) have been identified in adult human myocardium and contribute to overall tissue maintenance, with previous work identifying negative impact...

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Bibliographic Details
Main Authors: Robert Walmsley, Derek S. Steele, Sotiris Papaspyros, Andrew J. Smith
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Current Research in Toxicology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666027X24000203