Inhibitors of Rho/MRTF/SRF Transcription Pathway Regulate Mitochondrial Function

Inhibitors of Rho/MRTF/SRF Transcription Pathway Regulate Mitochondrial Function

RhoA-regulated gene transcription by serum response factor (SRF) and its transcriptional cofactor myocardin-related transcription factors (MRTFs) signaling pathway has emerged as a promising therapeutic target for pharmacological intervention in multiple diseases. Altered mitochondrial metabolism is...

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Manylion Llyfryddiaeth
Prif Awduron: Pankaj Patyal, Xiaomin Zhang, Ambika Verma, Gohar Azhar, Jeanne Y. Wei
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: MDPI AG 2024-02-01
Cyfres:Cells
Pynciau:
Rho/MRTF/SRF
mitochondria
bioenergetics
histone-4
acetylation
oxidative stress
Mynediad Ar-lein:https://www.mdpi.com/2073-4409/13/5/392

Rhyngrwyd

https://www.mdpi.com/2073-4409/13/5/392

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