Polymeric nanoparticles based topical gel of poorly soluble drug: Formulation, ex-vivo and in vivo evaluation

The study was conducted to evaluate the potential application of nanocapsules and nanospheres as topical drug delivery systems for indomethacin (as model drug). Both were prepared by nanoprecipitation using poly (ɛ-caprolactone) and hydroxypropyl β-cyclodextrin polymers and evaluated for morphology,...

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Bibliographic Details
Main Authors: Mohammed Elmowafy, Ahmed Samy, Abdelaziz E. Abdelaziz, Khaled Shalaby, Ayman Salama, Mohamed A. Raslan, Mohamed A. Abdelgawad
Format: Article
Language:English
Published: SpringerOpen 2017-06-01
Series:Beni-Suef University Journal of Basic and Applied Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2314853516301688