Highly congested spiro-compounds via photoredox-mediated dearomative annulation cascade

Photo-mediated radical dearomatization involving 5-exo-trig cyclizations has proven to be an important route to accessing spirocyclic compounds, whereas 6-exo-trig spirocyclization has been much less explored. Here, a dearomative annulation cascade is realized through a photoredox-mediated C–O bond...

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Bibliographic Details
Main Authors: Chao Zhou, Andrey Shatskiy, Azamat Z. Temerdashev, Markus D. Kärkäs, Peter Dinér
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-022-00706-3