Peripheral gene interactions define interpretable clusters of core ASD genes in a network-based investigation of the omnigenic theory
Abstract According to the recently proposed omnigenic theory, all expressed genes in a relevant tissue are contributing directly or indirectly to the manifestation of complex disorders such as autism. Thus, holistic approaches can be complementary in studying genetics of these complex disorders to f...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-08-01
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Series: | npj Systems Biology and Applications |
Online Access: | https://doi.org/10.1038/s41540-022-00240-x |