Peripheral gene interactions define interpretable clusters of core ASD genes in a network-based investigation of the omnigenic theory

Abstract According to the recently proposed omnigenic theory, all expressed genes in a relevant tissue are contributing directly or indirectly to the manifestation of complex disorders such as autism. Thus, holistic approaches can be complementary in studying genetics of these complex disorders to f...

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Bibliographic Details
Main Authors: Ábel Fóthi, Csaba Pintér, Péter Pollner, András Lőrincz
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-022-00240-x